Liverpool Ocular Oncology<br />Research Group
 
  • HOME
  • NEWS
  • Research Team
  • Disease Focus and Research
    • Uveal Melanoma
    • Conjunctival melanoma
    • Ocular Adnexal Lymphoma
  • Molecular Pathology
  • Ocular Oncology Biobank (OOB)
  • Paper Publications
    • 2025
    • 2024
    • 2023
    • 2022
    • 2021
    • 2020
    • 2019
    • 2018
    • 2017
    • 2016
    • 2015
    • 2014
    • 2013
    • 2012
    • 2011
    • 2010
    • 2009
    • 2008
    • 2007
    • 2006
    • 2005
    • 2004
  • Book Chapters
  • Informative Videos
  • Alumni
    • Previous Staff
    • Past PhD Students
    • Past MD Students
    • Past MRes Students
    • Past BSc/MSc Students
    • Nuffield Students
  • Visitors
    • Visiting researchers and clinicians
    • Visiting Students
    • Patients & Public
  • Support Us/Donations
  • Fundraising Events
  • Training and Opportunities
  • Contact us
  • Links

LOORG study takes us a step closer to understanding the spread of uveal melanoma

5/2/2013

 
Picture
Dr Sarah Lake
Congratulations to Dr Sarah Lake for the publication of her article “Single Nucleotide Polymorphism Array Analysis of Uveal Melanomas Reveals That Amplification of CNKSR3 Is Correlated With Improved Patient Survival”
(published in the American Journal of Pathology,  Jan 25th 2013).

Uveal melanoma patients whose tumours have lost one copy of the third largest chromosome, number 3, are at a high-risk of their disease spreading. Using a high-resolution assay, called SNP microarray, Dr Lake has determined that if these patients have a greater number of copies of the CNKSR3 gene, and consequently more of the protein, they live longer with their disease.   Dr Lake is now investigating how CNKSR3 may act within the cells as a “brake” to limit the spread of uveal melanoma cells.


Comments are closed.
Powered by Create your own unique website with customizable templates.