Dr Sarah Lake
Congratulations to Dr Sarah Lake for the publication of her article “Single Nucleotide Polymorphism Array Analysis of Uveal Melanomas Reveals That Amplification of CNKSR3 Is Correlated With Improved Patient Survival”
(published in the American Journal of Pathology, Jan 25th 2013).
Uveal melanoma patients whose tumours have lost one copy of the third largest chromosome, number 3, are at a high-risk of their disease spreading. Using a high-resolution assay, called SNP microarray, Dr Lake has determined that if these patients have a greater number of copies of the CNKSR3 gene, and consequently more of the protein, they live longer with their disease. Dr Lake is now investigating how CNKSR3 may act within the cells as a “brake” to limit the spread of uveal melanoma cells.
(published in the American Journal of Pathology, Jan 25th 2013).
Uveal melanoma patients whose tumours have lost one copy of the third largest chromosome, number 3, are at a high-risk of their disease spreading. Using a high-resolution assay, called SNP microarray, Dr Lake has determined that if these patients have a greater number of copies of the CNKSR3 gene, and consequently more of the protein, they live longer with their disease. Dr Lake is now investigating how CNKSR3 may act within the cells as a “brake” to limit the spread of uveal melanoma cells.