2020
Validation Of The Newly Proposed Who Classification System For Conjunctival Melanocytic Intraepithelial Lesions: A Comparison With The 'C-MIN' And 'PAM' Classification Schemes.
Milman T, Eiger-Moscovich M, Henry RK, Folberg R, Coupland SE, Grossniklaus HE, Mudhar HS, Eberhart CG, Heegaard S, Auw-Hädrich C, Herwig-Carl MC, Löffler KU, Cherepanoff S, Zhang Q, Sharpe JE, See TRO, Shields CL, Eagle RC Jr.
Am J Ophthalmol. 2020 Oct 29:S0002-9394(20)30588-2. doi: 10.1016/j.ajo.2020.10.020.
online ahead of print.PMID: 33130046
Milman T, Eiger-Moscovich M, Henry RK, Folberg R, Coupland SE, Grossniklaus HE, Mudhar HS, Eberhart CG, Heegaard S, Auw-Hädrich C, Herwig-Carl MC, Löffler KU, Cherepanoff S, Zhang Q, Sharpe JE, See TRO, Shields CL, Eagle RC Jr.
Am J Ophthalmol. 2020 Oct 29:S0002-9394(20)30588-2. doi: 10.1016/j.ajo.2020.10.020.
online ahead of print.PMID: 33130046
Leukotriene B4 (LTB4) and its receptor in Experimental Autoimmune Uveitis (EAU) and in human retinal tissues: clinical severity and LTB4-dependence of retinal Th17 cells.
Eskandarpour M, Chen YH, Nunn MA, Coupland SE, Weston-Davies W, Calder VL.
Am J Pathol. 2020 Nov 4:S0002-9440(20)30491-0. doi: 10.1016/j.ajpath.2020.10.010.
Online ahead of print.PMID: 33159884
Am J Pathol. 2020 Nov 4:S0002-9440(20)30491-0. doi: 10.1016/j.ajpath.2020.10.010.
Online ahead of print.PMID: 33159884
Optic nerve head sarcoidosis mimicking an intraocular tumour, and occurring as the first manifestation of neuro-ocular sarcoidosis
Yamini Krishna Louise Christou Jakub Khzouz Rumana Hussain Heinrich Heimann Sarah E. Coupland
https://doi.org/10.1016/j.ajoc.2020.100988
https://doi.org/10.1016/j.ajoc.2020.100988
The reproduction of human pathology specimens using three-dimensional (3D) printing technology for teaching purposes.
McMenamin PG, Hussey D, Chin D, Alam W, Quayle MR, Coupland SE, Adams JW.
Med Teach. 2020 Oct 26:1-9.
doi: 10.1080/0142159X.2020.1837357. Online ahead of print.PMID: 33103933
Med Teach. 2020 Oct 26:1-9.
doi: 10.1080/0142159X.2020.1837357. Online ahead of print.PMID: 33103933
Validation Of The Newly Proposed Who Classification System For Conjunctival Melanocytic Intraepithelial Lesions: A Comparison With The 'C-MIN' And 'PAM' Classification Schemes.
Milman T, Eiger-Moscovich M, Henry RK, Folberg R, Coupland SE, Grossniklaus HE, Mudhar HS, Eberhart CG, Heegaard S, Auw-Hädrich C, Herwig-Carl MC, Löffler KU, Cherepanoff S, Zhang Q, Sharpe JE, See TRO, Shields CL, Eagle RC Jr.
Am J Ophthalmol. 2020 Oct 29:S0002-9394(20)30588-2. doi: 10.1016/j.ajo.2020.10.020.
online ahead of print.PMID: 33130046
Milman T, Eiger-Moscovich M, Henry RK, Folberg R, Coupland SE, Grossniklaus HE, Mudhar HS, Eberhart CG, Heegaard S, Auw-Hädrich C, Herwig-Carl MC, Löffler KU, Cherepanoff S, Zhang Q, Sharpe JE, See TRO, Shields CL, Eagle RC Jr.
Am J Ophthalmol. 2020 Oct 29:S0002-9394(20)30588-2. doi: 10.1016/j.ajo.2020.10.020.
online ahead of print.PMID: 33130046
High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells
by Kayleigh Slater 1,2, Aisling B. Heeran 3, Sandra Garcia-Mulero 4,5, Helen Kalirai 6, Rebeca Sanz-Pamplona 4, Arman Rahman 1, Nebras Al-Attar 1, Mays Helmi 7, Fiona O’Connell 3, Rosa Bosch 8, Anna Portela 8, Alberto Villanueva 8, William M. Gallagher 1, Lasse D. Jensen 7, Josep M. Piulats 9,10, Sarah E. Coupland 6,11, Jacintha O’Sullivan 3 and Breandán N. Kennedy 1,*
by Kayleigh Slater 1,2, Aisling B. Heeran 3, Sandra Garcia-Mulero 4,5, Helen Kalirai 6, Rebeca Sanz-Pamplona 4, Arman Rahman 1, Nebras Al-Attar 1, Mays Helmi 7, Fiona O’Connell 3, Rosa Bosch 8, Anna Portela 8, Alberto Villanueva 8, William M. Gallagher 1, Lasse D. Jensen 7, Josep M. Piulats 9,10, Sarah E. Coupland 6,11, Jacintha O’Sullivan 3 and Breandán N. Kennedy 1,*
- PMID: 33066024
- DOI: 10.3390/cancers12102950
Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma.
Krishna Y, Acha-Sagredo A, Sabat-Pośpiech D, Kipling N, Clarke K, Figueiredo CR, Kalirai H,Coupland SE.
Cancers (Basel). 2020 Sep 30;12(10):E2832. doi: 10.3390/cancers12102832.
PMID: 33008022
Cancers (Basel). 2020 Sep 30;12(10):E2832. doi: 10.3390/cancers12102832.
PMID: 33008022
Conditional Survival in Uveal Melanoma.
Zabor EC, Radivoyevitch T, Singh AD, Kilic E, de Klein JEMM, Kalirai H, Coupland SE.
Ophthalmol Retina. 2020 Sep 23:S2468-6530(20)30395-X. doi: 10.1016/j.oret.2020.09.015.
Online ahead of print.PMID: 3297955 PDF VERSION
Ophthalmol Retina. 2020 Sep 23:S2468-6530(20)30395-X. doi: 10.1016/j.oret.2020.09.015.
Online ahead of print.PMID: 3297955 PDF VERSION
Conjunctival melanoma treatment outcomes in 288 patients: a multicentre international data-sharing study
Puneet Jain 1 , Paul T Finger 2 , Maria Fili 3 , Bertil Damato 4 , Sarah E Coupland 5 , Heinrich Heimann 5 , Nihal Kenawy 6 , Niels J Brouwer 7 , Marina Marinkovic 7 , Sjoerd G Van Duinen 7 , Jean Pierre Caujolle 8 , Celia Maschi 8 , Stefan Seregard 3 , David Pelayes 9 , Martin Folgar 9 , Yacoub A Yousef 10 , Hatem Krema 11 , Brenda Gallie 11 , Alberto Calle-Vasquez 12 , American Joint Committee on Cancer Ophthalmic Oncology Task Force
PMID: 32892167 DOI: 10.1136/bjophthalmol-2020-316293
Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections
Translational Vision Science & Technology September 2020, Vol.9, 50. doi:https://doi.org/10.1167/tvst.9.2.50
MicroRNAs and Uveal Melanoma: Understanding the Diverse Role of These Small Molecular Regulators
by Karen Aughton 1,*, Helen Kalirai 1,2 and Sarah E. Coupland 1,2
*Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(16), 5648; https://doi.org/10.3390/ijms21165648
Received: 16 July 2020 / Revised: 31 July 2020 / Accepted: 4 August 2020 / Published: 6 August 2020
(This article belongs to the Special Issue Genetic Basis and Molecular Mechanisms of Uveal Melanomas)
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Melanoblasts Populate the Mouse Choroid Earlier in Development Than Previously Described
Paul G. McMenamin; Graham T. Shields; Yashar Seyed-Razavi; Helen Kalirai; Robert H. Insall; Laura M. Machesky; Sarah E. Coupland
Investigative Ophthalmology & Visual Science August 2020, Vol.61, 33. doi:https://doi.org/10.1167/iovs.61.10.33
Paul G. McMenamin; Graham T. Shields; Yashar Seyed-Razavi; Helen Kalirai; Robert H. Insall; Laura M. Machesky; Sarah E. Coupland
Investigative Ophthalmology & Visual Science August 2020, Vol.61, 33. doi:https://doi.org/10.1167/iovs.61.10.33
Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture
Aughton K, Shahidipour H, Djirackor L, Coupland SE, Kalirai H.
Trans Vis Sci Tech. 2020;9(7):39
https://doi.org/10.1167/tvst.9.7.39
Aughton K, Shahidipour H, Djirackor L, Coupland SE, Kalirai H.
Trans Vis Sci Tech. 2020;9(7):39
https://doi.org/10.1167/tvst.9.7.39
Iris lymphoma - a systematic guide for diagnosis and treatment.
Kakkassery V, Coupland SE, Heindl LM.
Surv Ophthalmol. 2020 Jun 22:S0039-6257(20)30100-4. doi: 10.1016/j.survophthal.2020.06.003. Online ahead of print.
Lymphoma of the lacrimal gland - An International Multicenter Retrospective Study. Vest SD, Mikkelsen LH, Holm F, Rasmussen PK, Hindso TG, Knudsen MKH, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Mulay K, Sjö LD, Sniegowski ME, Vemuganti GK, Thuro BA, Heegaard S.Am J Ophthalmol. 2020 Jun 20:S0002-9394(20)30311-1. doi: 10.1016/j.ajo.2020.06.015. Online ahead of print.PMID: 32574779
Image Analysis 3D Conjunctival Melanoma Cell Cultures Following Electrochemotherapy
Miltiadis Fiorentzis, Periklis Katopodis, Helen Kalirai, Berthold Seitz, Arne Viestenz and Sarah E. Coupland
Received: 25 April 2020; Accepted: 9 June 2020; Published: 13 June 2020
Ano-uro-genital mucosal melanoma UK national guidelines
Henry G Smith, Izhar Bagwan, Ruth E Board, Sharon Capper, Sarah E Coupland, Jessica Glen, Susan Lalondrelle, Antonia Mayberry, Asif Muneer, Karen Nugent, Pubudu Pathiraja, Miranda Payne, Howard Peach, Jonathan Smith, Sarah Westwell, Ewan Wilson, Simon Rodwell, Martin Gore, Nancy Turnbull, Myles J F Smith
Spontaneous Necrosis of a Large Choroidal Melanoma: Unusual Presentation in a 49-Year-Old Male
Baumann C, Iannetta D, Coupland SE, Groenewald C, Vishwanath M, Heimann H.Ocul Oncol Pathol. 2020 May;6(3):174-179. doi: 10.1159/000501522. Epub 2019 Dec 5.PMID: 32509762
Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition
Adriana Amaro, Michela Croce, Silvano Ferrini, Gaia Barisione, Marina Gualco, Patrizia Perri, Ulrich Pfeffer,
Martine J Jager, Sarah E Coupland, Carlo Mosci, Gilberto Filaci, Marina Fabbi, Paola Queirolo, Rosaria Gangemi.
Cancers 2020, 12(6), 1468; https://doi.org/10.3390/cancers12061468 (registering DOI)
Received: 18 May 2020 / Revised: 1 June 2020 / Accepted: 2 June 2020 / Published: 4 June 2020
Martine J Jager, Sarah E Coupland, Carlo Mosci, Gilberto Filaci, Marina Fabbi, Paola Queirolo, Rosaria Gangemi.
Cancers 2020, 12(6), 1468; https://doi.org/10.3390/cancers12061468 (registering DOI)
Received: 18 May 2020 / Revised: 1 June 2020 / Accepted: 2 June 2020 / Published: 4 June 2020
Inhibition of ATM Increases the Radiosensitivity of Uveal Melanoma Cells to Photons and Protons
Rumana N. Hussain, Sarah E. Coupland, Jakub Khzouz, Helen Kalirai, Jason L. Parsons
Open Access Article
Cancers 2020
(This article belongs to the Special Issue Proton Therapy For Cancers)
Open Access Article
Cancers 2020
(This article belongs to the Special Issue Proton Therapy For Cancers)
Primary Vitreoretinal Lymphoma in HIV Infection
Jonel Steffen, Sarah E. Coupland & Justine R. Smith
To cite this article: Jonel Steffen, Sarah E. Coupland & Justine R. Smith (2020):
Primary Vitreoretinal Lymphoma in HIV Infection, Ocular Immunology and Inflammation,
DOI:10.1080/09273948.2020.1751856
Published online: 26 May 2020.
To cite this article: Jonel Steffen, Sarah E. Coupland & Justine R. Smith (2020):
Primary Vitreoretinal Lymphoma in HIV Infection, Ocular Immunology and Inflammation,
DOI:10.1080/09273948.2020.1751856
Published online: 26 May 2020.
Targeted Next-Generation Sequencing of 117 Routine Clinical Samples Provides Further Insights into the Molecular Landscape of Uveal Melanoma
Sophie Thornton, Sarah E. Coupland, Lisa Olohan, Julie S. Sibbring, John G. Kenny, Christiane Hertz-Fowler, Xuan Liu, Sam Haldenby, Heinrich Heimann, Rumana Hussain, Natalie Kipling, Azzam Taktak, Helen Kalirai.
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Browse Figures
Parsimonious Models for Predicting Mortality from Choroidal Melanoma.
Damato B, Eleuteri A, Hussain R, Kalirai H, Thornton S, Taktak A, Heimann H, Coupland SE.
Invest Ophthalmol Vis Sci. 2020 Apr 9;61(4):35. doi: 10.1167/iovs.61.4.35.PMID: 32334433
Invest Ophthalmol Vis Sci. 2020 Apr 9;61(4):35. doi: 10.1167/iovs.61.4.35.PMID: 32334433
Electrochemotherapy in 3D ocular melanoma spheroids using a customized electrode.
Fiorentzis, M., Viestenz, A., Seitz, B., Coupland, S. E., Heinzelmann, J.
J. Vis. Exp. (158), e60611, doi:10.3791/60611 (2020).
www.jove.com/pdf/60611/jove-protocol-60611-electrochemotherapy-3d-ocular-melanoma-spheroids-using-customized
Fiorentzis, M., Viestenz, A., Seitz, B., Coupland, S. E., Heinzelmann, J.
J. Vis. Exp. (158), e60611, doi:10.3791/60611 (2020).
www.jove.com/pdf/60611/jove-protocol-60611-electrochemotherapy-3d-ocular-melanoma-spheroids-using-customized
A possible role for hepcidin in the detection of iron deficiency in severely anaemic HIV-infected patients in Malawi.
Huibers MHW, Calis JC, Allain TJ, Coupland SE, Phiri C, Phiri KS, Swinkels DW, Boele van Hensbroek M, Bates I.
PLoS One. 2020 Feb 27;15(2):e0218694. doi: 10.1371/journal.pone.0218694. eCollection 2020.
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Severe anaemia complicating HIV in Malawi; Multiple co-existing aetiologies are associated with high mortality.
Huibers MHW, Bates I, McKew S, Allain TJ, Coupland SE, Phiri C, Phiri KS, Boele van Hensbroek M, Calis JC.
PLoS One. 2020 Feb 25;15(2):e0218695. doi: 10.1371/journal.pone.0218695. eCollection 2020
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Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator Online: An OOG Collaborative Study.
Cunha Rola A, Taktak A, Eleuteri A, Kalirai H, Heimann H, Hussain R, Bonnett LJ, Hill CJ, Traynor M, Jager MJ, Marinkovic M, Luyten GPM, Dogrusöz M, Kilic E, de Klein A, Smit K, van Poppelen NM, Damato BE, Afshar A, Guthoff RF, Scheef BO, Kakkassery V, Saakyan S, Tsygankov A, Mosci C, Ligorio P, Viaggi S, Le Guin CHD, Bornfeld N, Bechrakis NE, Coupland SE.
Cancers (Basel). 2020 Feb 18;12(2). pii: E477. doi: 10.3390/cancers12020477
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Lenalidomide, dexamethasone and alemtuzumab or ofatumumab in high-risk chronic lymphocytic leukaemia: final results of the NCRI CLL210 trial.
Pettitt AR, Jackson R, Cicconi S, Polydoros F, Yap C, Dodd J, Bickerstaff M, Stackpoole M, Khan UT, Carruthers S, Oates M, Lin K, Coupland SE, Menon G, Kalakonda N, McCarthy H, Bloor A, Schuh A, Duncombe A, Dearden C, Fegan C, Kennedy B, Walewska R, Marshall S, Fox CP, Hillmen P.
Haematologica. 2020 Feb 13. pii: haematol.2019.230805. doi: 10.3324/haematol.2019.230805. [Epub ahead of print]
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Huibers MHW, Calis JC, Allain TJ, Coupland SE, Phiri C, Phiri KS, Swinkels DW, Boele van Hensbroek M, Bates I.
PLoS One. 2020 Feb 27;15(2):e0218694. doi: 10.1371/journal.pone.0218694. eCollection 2020.
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Severe anaemia complicating HIV in Malawi; Multiple co-existing aetiologies are associated with high mortality.
Huibers MHW, Bates I, McKew S, Allain TJ, Coupland SE, Phiri C, Phiri KS, Boele van Hensbroek M, Calis JC.
PLoS One. 2020 Feb 25;15(2):e0218695. doi: 10.1371/journal.pone.0218695. eCollection 2020
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Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator Online: An OOG Collaborative Study.
Cunha Rola A, Taktak A, Eleuteri A, Kalirai H, Heimann H, Hussain R, Bonnett LJ, Hill CJ, Traynor M, Jager MJ, Marinkovic M, Luyten GPM, Dogrusöz M, Kilic E, de Klein A, Smit K, van Poppelen NM, Damato BE, Afshar A, Guthoff RF, Scheef BO, Kakkassery V, Saakyan S, Tsygankov A, Mosci C, Ligorio P, Viaggi S, Le Guin CHD, Bornfeld N, Bechrakis NE, Coupland SE.
Cancers (Basel). 2020 Feb 18;12(2). pii: E477. doi: 10.3390/cancers12020477
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Pettitt AR, Jackson R, Cicconi S, Polydoros F, Yap C, Dodd J, Bickerstaff M, Stackpoole M, Khan UT, Carruthers S, Oates M, Lin K, Coupland SE, Menon G, Kalakonda N, McCarthy H, Bloor A, Schuh A, Duncombe A, Dearden C, Fegan C, Kennedy B, Walewska R, Marshall S, Fox CP, Hillmen P.
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Effects of plaque brachytherapy and proton beam radiotherapy on prognostic testing: a comparison of uveal melanoma genotyped by microsatellite analysis.
Thornton S, Coupland SE, Heimann H, Hussain R, Groenewald C, Kacperek A, Damato B, Taktak A, Eleuteri A, Kalirai H. Br J Ophthalmol. 2020 Feb 5. pii: bjophthalmol-2019-315363. doi: 10.1136/bjophthalmol-2019-315363.
Thornton S, Coupland SE, Heimann H, Hussain R, Groenewald C, Kacperek A, Damato B, Taktak A, Eleuteri A, Kalirai H. Br J Ophthalmol. 2020 Feb 5. pii: bjophthalmol-2019-315363. doi: 10.1136/bjophthalmol-2019-315363.
Software-assisted decision support in digital histopathology.
Huss R, Coupland SE.
J Pathol. 2020 Jan 28. doi: 10.1002/path.5388. [Epub ahead of print] Review.
Huss R, Coupland SE.
J Pathol. 2020 Jan 28. doi: 10.1002/path.5388. [Epub ahead of print] Review.
Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.
Figueiredo CR, Kalirai H, Sacco JJ, Azevedo RA, Duckworth A, Slupsky JR, Coulson JM, Coupland SE.
Journal of Pathology. 2020 Apr;250(4):420-439.doi: 10.1002/path.5384.
Figueiredo CR, Kalirai H, Sacco JJ, Azevedo RA, Duckworth A, Slupsky JR, Coulson JM, Coupland SE.
Journal of Pathology. 2020 Apr;250(4):420-439.doi: 10.1002/path.5384.
