Ocular Oncology Biobank (OOB)
The University of Liverpool, Ocular Oncology Biobank (OOB) is a resource of tissue and blood samples donated by patients with eye cancer for use in research. The OOB provides a simple and efficient way to collect and store samples according to regulatory requirements and it ensures that a high quality resource from patients with rare ocular tumours is available to researchers; from which they can draw substantial linked collections of material and associated clinical data.
The OOB operates under HTA Licence 12020 and HRA REC 11/NW/0249
The Biobank is closely associated with the Liverpool Ocular Oncology Centre, one of only three specialist centres for patients with eye cancer in England. This ensures that patients with rare conditions such as ocular tumours are given the highest possible standard of care by an experienced specialist team.
Samples are used for research studies, which may contribute to increasing the knowledge and understanding of eye cancer in order to improve treatment, and ultimately patient care. Currently supported studies within the LOORG include:
• HRA REC Ref 11-NW-0759; Molecular characteristics of metastatic liver lesions in uveal melanoma: the search for therapeutic targets
• HRA REC Ref 11-NW-0568; Identification of biomarkers of metastatic disease
• HRA REC Ref 15-SS-0097; Development of cell based in vitro and in vivo models of uveal melanoma
• HRA REC Ref 15-SC-0611; Enhancing Prognostication in Uveal Melanoma
• HRA REC Ref 16-SW-0112; BAP1 and Histone Deacetylase expression in Uveal Melanoma
If you would like more information about the OOB then please contact the biosample custodian:
Dr Helen Kalirai
Liverpool Ocular Oncology Research Group
Department of Molecular and Clinical Cancer Medicine
University of Liverpool
Tel: 0151 794 9117